Figure 1
From: Identification of linear human B-cell epitopes of tick-borne encephalitis virus
SPOT array of TBEV proteome as overlapping peptides and prediction of antigenic regions. A) SPOT array of TBEV coding region, acute TBEV-seropositive pool spots in rectangle, TBEV-immunized spots in circles, i) acute TBEV-seropositive serum pool, ii) TBEV-seronegative serum pool and iii) TBEV-immunized serum pool. B) Kyte and Doolittle hydrophilicity plot of the TBEV genome corresponds to the signal intensities from the TBEV-seropositive and –negative serum pools. The window in Kyte and Doolittle hydrophilicity plot is 18. Amino acids in X-axis, signal intensities of the SPOT array in Y (TBEV-seropositive in blue, TBEV-seronegative in red), hydrophilicity (above) and hydrophobicity (below) in the upper X-axis.