Skip to main content

Table 1 Virological properties of vectors

From: A recombinant adenovirus-based vector elicits a specific humoral immune response against the V3 loop of HIV-1 gp120 in mice through the “Antigen Capsid-Incorporation” strategy

Modified vectors

VP

Infectious Particles (IP)

VP/IP

Ad

3.1 × 1012 VP/ml

1.0 × 1011 IP/ml

31

Ad-HVR1-lgs-His6-V3

3.0 × 1012 VP/ml

7.9× 1010 IP/ml

37

Ad-HVR1-V3

1.4 × 1012 VP/ml

4.0 × 106 IP/ml

3.5 × 105

Ad-HVR1-long-V3

1.9 × 1012 VP/ml

3.0 × 1010 IP/ml

63

Ad-HVR1-lgs-V3-His6-lgs

5.5 × 1011 VP/ml

2.8 × 106 IP/ml

1.9 × 105

  1. All vectors are serotype and hexon 5-based.