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Table 1 Virological properties of vectors

From: A recombinant adenovirus-based vector elicits a specific humoral immune response against the V3 loop of HIV-1 gp120 in mice through the “Antigen Capsid-Incorporation” strategy

Modified vectors VP Infectious Particles (IP) VP/IP
Ad 3.1 × 1012 VP/ml 1.0 × 1011 IP/ml 31
Ad-HVR1-lgs-His6-V3 3.0 × 1012 VP/ml 7.9× 1010 IP/ml 37
Ad-HVR1-V3 1.4 × 1012 VP/ml 4.0 × 106 IP/ml 3.5 × 105
Ad-HVR1-long-V3 1.9 × 1012 VP/ml 3.0 × 1010 IP/ml 63
Ad-HVR1-lgs-V3-His6-lgs 5.5 × 1011 VP/ml 2.8 × 106 IP/ml 1.9 × 105
  1. All vectors are serotype and hexon 5-based.