Figure 1From: Comparative quantitative monitoring of rabbit haemorrhagic disease viruses in rabbit kittensRHDV replication and excretion in rabbit kittens, which survived and seroconverted. Rabbit kittens 4–5 weeks of age were infected with 700 ID50 of RHDV-v351 as determined in adults and virus replication and shedding was monitored via real-time PCR analysis of virus genome copy numbers in blood and swab samples taken at the indicated times post infection. A: Virus genome copy numbers per μl whole blood and B: virus genome copy numbers per swab sample. The copy lowest copy numbers that could be accurately detected with the amount of template used in the assay is indicated (SDL = safe detection limit). Serum IgM (C) and IgG titres (D) were determined in blood samples taken at the indicated times after infection via ELISA as described previously [54, 55].Back to article page