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Table 1 Assessment of specific (binding) antibody to NiV soluble-G and neutralising antibody at day 21 post-exposure

From: Subclinical infection without encephalitis in mice following intranasal exposure to Nipah virus-Malaysia and Nipah virus-Bangladesh

Virus strain Mouse strain Age Mouse # Binding antibody to NiV sG^ Serum neutralisation
Nipah Malaysia BALB/c YA* 1 + -
2 + -
3 + -
4 + -
5 + -
Aged 6 + -
7 - -
8 + -
9 + -
10 + -
C57BL/6 YA 11 + -
12 + -
13 + -
14 + -
Aged 15 + -
16 + -
17 - -
18 + -
Nipah Bangladesh BALB/c YA 19 + -
20 + -
21 + -
22 + -
23 - -
Aged 24 - -
25 + -
26 + -
27 + -
28 + -
C57BL/6 YA 29 - -
30 - -
31 + -
32 - -
33 + -
Aged 34 - -
35 - -
36 - -
37 - -
  1. ^sG = soluble-G, *YA = Young adult, for binding antibody to NiV sG (+) was defined as a four fold or greater increase in median fluorescence intensity from pre-challenge levels, for serum neutralisation (−) indicates that no neutralising antibody was detected.