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Table 1 Assessment of specific (binding) antibody to NiV soluble-G and neutralising antibody at day 21 post-exposure

From: Subclinical infection without encephalitis in mice following intranasal exposure to Nipah virus-Malaysia and Nipah virus-Bangladesh

Virus strain

Mouse strain

Age

Mouse #

Binding antibody to NiV sG^

Serum neutralisation

Nipah Malaysia

BALB/c

YA*

1

+

-

2

+

-

3

+

-

4

+

-

5

+

-

Aged

6

+

-

7

-

-

8

+

-

9

+

-

10

+

-

C57BL/6

YA

11

+

-

12

+

-

13

+

-

14

+

-

Aged

15

+

-

16

+

-

17

-

-

18

+

-

Nipah Bangladesh

BALB/c

YA

19

+

-

20

+

-

21

+

-

22

+

-

23

-

-

Aged

24

-

-

25

+

-

26

+

-

27

+

-

28

+

-

C57BL/6

YA

29

-

-

30

-

-

31

+

-

32

-

-

33

+

-

Aged

34

-

-

35

-

-

36

-

-

37

-

-

  1. ^sG = soluble-G, *YA = Young adult, for binding antibody to NiV sG (+) was defined as a four fold or greater increase in median fluorescence intensity from pre-challenge levels, for serum neutralisation (−) indicates that no neutralising antibody was detected.