Table 4 List of clinically relevant mutations detected in the S ORF of the HBV complete genome sequences acquired in this study
From: A description of the hepatitis B virus genomic background in a high-prevalence area in China
Genotype B | Genotype C | Genotype D | Total number | |
|---|---|---|---|---|
No of sequences | 43 | 145 | 54 | 242 |
preS1 deletion mutation** | 0 | 5 | 11 | 16 |
preS2 deletion mutation | 1 | 4 | 0 | 5 |
G129H/R | 1 | 5 | 2 | 8 |
G145R | 1 | 4 | 0 | 5 |
T126A/S | 1 | 1 | 1 | 3 |
P127T | 0 | 4 | 2 | 6 |
G130R | 1 | 2 | 0 | 3 |
T131P | 2 | 5 | 2 | 9 |
M134Y | 11 | 31 | 14 | 56 |
S143T/L | 8 | 20 | 11 | 39 |