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Figure 2 | Virology Journal

Figure 2

From: Nitazoxanide inhibits the replication of Japanese encephalitis virus in cultured cells and in a mouse model

Figure 2

Analysis of the effect of NTZ on the formation of JEV-induced CPE. (A) BHK-21 cells were treated with the indicated concentrations of NTZ for 48 h and the cytotoxicity of NTZ was analyzed by MTT assay. DMSO-treated cells were used as a control. The data are means with SD from three independent experiments. (B) BHK-21 cells were infected with JEV at a MOI of 0.001. After a 1 h adsorption period, the cells were treated with NTZ at the indicated concentrations and incubated for 48 h. The JEV-induced CPE was examined under a light microscope.

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