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Table 1 Functional gene ontology annotation using DAVID

From: Transcriptional analysis of the innate immune response of ducks to different species-of-origin low pathogenic H7 avian influenza viruses

Up-regulated

 

Down-regulated

 

Pathway

%

P value

Pathway

%

P value

gga04142:Lysosome

3.32

0.0155

gga04520:Adherens junction

2.97

0.0000

gga00190:Oxidative phosphorylation

3.32

0.0420

gga04060:Cytokine-cytokine receptor interaction

2.97

0.0456

gga04620:Toll-like receptor signaling pathway

2.90

0.0213

gga03010:Ribosome

2.75

0.0004

gga04621:NOD-like receptor signaling pathway

2.07

0.0259

gga04514:Cell adhesion molecules (CAMs)

2.54

0.0153

   

gga04142:Lysosome

2.33

0.0300

   

gga04350:TGF-beta signaling pathway

1.91

0.0483

  1. The gene list containing the 559 up-regulated and 1198 down-regulated differentially expressed genes in duck spleen common to all three LPAIV infections at 3 dpi was entered into the DAVID functional annotation software. The following KEGG pathways are enriched in the dataset. The percentage column indicates percentage of differentially expressed genes that mapped to the DAVID database with a corresponding significance value (p<0.05).