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Table 1 Patient's characteristics according to HBV genotype

From: Epidemiological, virological and clinical characteristics of HBV infection in 223 HIV co-infected patients: a French multi-centre collaborative study

  Overall HBV Genotype  
   A D E G p value
Total number 223 116 36 52 15  
Male sex , n (%) 178 (81) 106 (91) 27 (77) 29 (58) 14 (93) <0.001
Mean age (sd) 41.9 (9.0) 43.4 (8.6) 43.5 (5.7) 37.2 (10.0) 44.1 (4.9) <0.001
Country of Origin       
Europe (107) 107 74 (77.1) 20 (74.1) 4 (9.3) 9 (69.2)  
North Africa (17) 17 9 (9.4) 4 (14.8) 0 4 (30.8)  
Subsaharan Africa (51) 51 10 (10.4) 2 (7.4) 39 (90.7) 0 <0.001
Asia (2) 5 1 (1.0) 1 (3.7) 0 0  
Other (2) 2 2 (2.1) 0 0 0  
Source of infection       
Mother-to-child 4 11.0 0 36.4 0  
Homosexual 85 69 (71.9) 5 (15.2) 1 (2.1) 9 (81.8)  
IVDU 22 1 (1.0) 20 (60.6) 1 (2.1) 0 <0.001
Heterosexual 73 20 (20.8) 8 (24.2) 41 (87.5) 2 (18.2)  
Other/unknown 6 5 (5.2) 0 1 (2.1) 0  
Hepatic disease       
ALT : med [IQR] 43 (29–64) 44.5 (30–64) 41.5 (27–99) 38.0 (28–53) 41.5 (38–92) 0.39
Metavir A >1 31/83 (37.3) 14 (35.9) 6 (42.9) 6 (28.6) 4 (50) 0.70
Metavir F ≥2 51/94 (54.3) 26 (57.8) 9 (60.0) 8 (34.8) 7 (77.8) 0.11
Cirrhosis 17/94 (18.1) 9/45 (20) 2/15 (13.3) 4/23 (17.4) 2/9 (22.2) 0.9
Viral markers       
HBe Ag + (%) 127/192 (66.1) 75 (78.9) 16 (48.5) 22 (45.8) 11 (91.7) <0.001
Anti HBe + (%) 56/192 (29.2) 18 (18.9) 13 (39.4) 24 (50) 0 <0.001
HBV VL log IU/mL 5.26 (3.91–7.4) 5.63 (4.2–7.6) 5.25 (3.7–7.7) 4.97 (3.8–6.5) 3.96 (3.3–7.3) 0.31
% with HBV VL > 2000 IU/mL 195 (87.4) 101 (87.1) 31 (86.1) 47 (90.4) 12 (80.0) 0.081
HCV + (%) 28/207 (13.5) 7 (6.5) 19 (54.3) 0 2 (14.3) <0.001
HDV + (%) 13/164 (7.9) 2 (2.4) 5 (21.7) 5 (11.1) 1 (7.7) 0.011
  1. (Unfrequent genotypes, 1 genotype B, 2 genotypes C and 1 genotype F, were not included in this analysis).