Table 1 Patient's characteristics according to HBV genotype
Overall | HBV Genotype | |||||
|---|---|---|---|---|---|---|
A | D | E | G | p value | ||
Total number | 223 | 116 | 36 | 52 | 15 | |
Male sex , n (%) | 178 (81) | 106 (91) | 27 (77) | 29 (58) | 14 (93) | <0.001 |
Mean age (sd) | 41.9 (9.0) | 43.4 (8.6) | 43.5 (5.7) | 37.2 (10.0) | 44.1 (4.9) | <0.001 |
Country of Origin | ||||||
Europe (107) | 107 | 74 (77.1) | 20 (74.1) | 4 (9.3) | 9 (69.2) | |
North Africa (17) | 17 | 9 (9.4) | 4 (14.8) | 0 | 4 (30.8) | |
Subsaharan Africa (51) | 51 | 10 (10.4) | 2 (7.4) | 39 (90.7) | 0 | <0.001 |
Asia (2) | 5 | 1 (1.0) | 1 (3.7) | 0 | 0 | |
Other (2) | 2 | 2 (2.1) | 0 | 0 | 0 | |
Source of infection | ||||||
Mother-to-child | 4 | 11.0 | 0 | 36.4 | 0 | |
Homosexual | 85 | 69 (71.9) | 5 (15.2) | 1 (2.1) | 9 (81.8) | |
IVDU | 22 | 1 (1.0) | 20 (60.6) | 1 (2.1) | 0 | <0.001 |
Heterosexual | 73 | 20 (20.8) | 8 (24.2) | 41 (87.5) | 2 (18.2) | |
Other/unknown | 6 | 5 (5.2) | 0 | 1 (2.1) | 0 | |
Hepatic disease | ||||||
ALT : med [IQR] | 43 (29–64) | 44.5 (30–64) | 41.5 (27–99) | 38.0 (28–53) | 41.5 (38–92) | 0.39 |
Metavir A >1 | 31/83 (37.3) | 14 (35.9) | 6 (42.9) | 6 (28.6) | 4 (50) | 0.70 |
Metavir F ≥2 | 51/94 (54.3) | 26 (57.8) | 9 (60.0) | 8 (34.8) | 7 (77.8) | 0.11 |
Cirrhosis | 17/94 (18.1) | 9/45 (20) | 2/15 (13.3) | 4/23 (17.4) | 2/9 (22.2) | 0.9 |
Viral markers | ||||||
HBe Ag + (%) | 127/192 (66.1) | 75 (78.9) | 16 (48.5) | 22 (45.8) | 11 (91.7) | <0.001 |
Anti HBe + (%) | 56/192 (29.2) | 18 (18.9) | 13 (39.4) | 24 (50) | 0 | <0.001 |
HBV VL log IU/mL | 5.26 (3.91–7.4) | 5.63 (4.2–7.6) | 5.25 (3.7–7.7) | 4.97 (3.8–6.5) | 3.96 (3.3–7.3) | 0.31 |
% with HBV VL > 2000 IU/mL | 195 (87.4) | 101 (87.1) | 31 (86.1) | 47 (90.4) | 12 (80.0) | 0.081 |
HCV + (%) | 28/207 (13.5) | 7 (6.5) | 19 (54.3) | 0 | 2 (14.3) | <0.001 |
HDV + (%) | 13/164 (7.9) | 2 (2.4) | 5 (21.7) | 5 (11.1) | 1 (7.7) | 0.011 |