Figure 4From: Quantitative prediction of integrase inhibitor resistance from genotype through consensus linear regression modelingPerformance of RAL second order model on external validation set. The R2 performance of the RAL second order model on the validation set containing 67 IN site-directed mutants (measured with PhenoSense assay) was 0.80. Three potential outliers were identified: 148K + 140S, 66I + 92Q and 143C + 97A. After outlier removal the R2 performance was 0.91 (dotted regression line). In the graph, site-directed mutants are classified according to the primary mutation harboured.Back to article page