Table 1 Possible epitopes for classes I and II HLA alleles in HTLV-1 gp46 175-209 aa domain

175

F

L

N

T

E

P

S

Q

L

A 0201, B 08

177

N

T

E

P

S

Q

L

P

P

A 01, A 1101, B 4501

179

E

P

S

Q

L

P

P

T

A

A 0702

182

Q

L

P

P

T

A

P

P

L

A 0201, B 08, B 4402

183

L

P

P

T

A

P

P

L

L

A 0701, B 08, B 5101

184

P

P

T

A

P

P

L

L

P

B 0702

185

P

T

A

P

P

L

L

P

H

A 1101

188

P

P

L

L

P

H

S

N

L

B 0702, B 02, B 1402, B 2705, B 37, B 5101

191

L

P

H

S

N

L

D

H

I

B 4901, B 5101

192

P

H

S

N

L

D

H

I

L

B 1510, B 3801 B 3901

193

H

S

N

L

D

H

I

L

E

A 1101

194

S

N

L

D

H

I

L

E

P

B 4501

199

I

L

E

P

S

I

P

W

K

A 03, A 1101, A 6801, B 2705

202

P

S

I

P

W

K

S

K

L

A 26, B 2705

203

S

I

P

W

K

S

K

L

L

A 0201, B 08, B 37

205

P

W

K

S

K

L

L

T

L

A 26, B 3901

B-Class II HLA alleles

AA position

Epitope sequence

HLA allele

172

P

I

W

F

L

N

T

E

P

S

Q

L

P

P

T

DRB 0701

180

P

S

Q

L

P

P

I

A

P

P

L

L

P

H

S

DRB 0301, DRB 0701

187

A

P

P

L

L

P

H

S

N

L

D

H

I

L

E

DRB 0301, DRB 1501

188

P

P

L

L

P

H

S

N

L

D

H

I

L

E

P

DRB 0701

193

H

S

N

L

D

H

I

L

E

P

S

I

P

W

K

DRB 0701

194

S

N

L

D

H

I

L

E

P

S

I

P

W

K

S

DRB1 0101

201

E

P

S

I

P

W

K

S

K

L

L

T

L

V

Q

DRB 1501