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Table 1 Cell types and description

From: A survey of ex vivo/in vitro transduction efficiency of mammalian primary cells and cell lines with Nine natural adeno-associated virus (AAV1-9) and one engineered adeno-associated virus serotype

Human Primary Cells

Description

BJ Fibroblasts

Foreskin fibroblasts

BJ hTERT Fibroblasts

Foreskin fibroblasts retrovirally infected with hTERT

ES cell

Embryonic stem cells

HUVEC

Human umbilical cord vein endothelial cells

Karatinocytes

Keratinocytes

Hematopoietic Progenitor

CD34+ umbilical cord cells

Human Cell Lines

Description

CaCo-2

Epithelial colorectal adenocarcinoma cells

HBEC

Human bronchial epithelial cells

HEK 293

Human embryonic kidney cells

HeLa

Cervical cancer cells

HepG2

Hepatocellular carcinoma

HT29

Colon adenocarcinoma grade II cells

Jurkat

immortalized line of T lymphocyte cells

K562

Myelogenous leukemia cells

MCF-7

Breast cancer cells

TF1a

Erthroleukemic cells

Saos-2

Osteosarcoma cells

U20S

Osteosarcoma cells

Mouse Primary Cells

Description

Adult Skin Fibroblast

Murine adult skin fibroblasts (MAFs)

Astrocytes

Astrocytes

ES cell

Embryonic stem cells

Hematopoietic Progenitor

cKit+, Sca+, Lin- hematopoietic cells

Keratinocytes

Keratinocytes

Lung Epithelial

Epithelial cells

Lung Mesenchymal

Mesenchymal cells

Mesenchymal Stem Cells

Mesenchymal stem cells

Embryonic Fibroblast

Murine embryonic fibroblasts (MEFs)

Skeletal Muscle Progenitor

Skeletal muscle progenitor cells

White Adipose Progenitor

White adipose progenitor cells

Mouse Cell Lines

Description

3 T3

Heterogeneous embryonic mouse cells

C2C12

Myoblast cells

MIN6

Pancreatic beta cells

Other Cell Lines

Description

CHO

Chinese hamster ovary cells

COS-7

African green monkey kidney fibroblasts

  1. Listed are the cell types transduced by AAV1-9 and AAV1.3 in Figures 2 and 3. The Materials and Methods section list a more detailed description of the primary cell isolations.