The input interface of the Mutation Reporter Tool. A FASTA input file of sequence data is specified. These sequence data (nucleotides or amino acids) may be genomic or subgenomic fragments. An “anchor motif”, which is common to all sequences, is provided. The “anchor position” specifies the genomic co-ordinate of the start of the “anchor motif”, such that the downstream loci of interest can be specified accordingly. In this figure, nine loci of interest have been specified. These nine loci will be grouped into columns according to the “output grouping” field: a column containing the first two loci, followed by a column containing the next four loci, followed by a column containing the final locus. Specific sequences in the input file can be included or excluded by entering a regular expression into the appropriate field. This field is blank in the figure, which indicates that all sequences will be included.