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Figure 2 | Virology Journal

Figure 2

From: Comparison of host cell gene expression in cowpox, monkeypox or vaccinia virus-infected cells reveals virus-specific regulation of immune response genes

Figure 2

CPXV- and MPXV- but not VACV-modulated cellular pathways are involved in infectious diseases. Cellular pathways that were significantly affected by infection with CPXV, MPXV or VACV, respectively, as indicated by * (p ≤ 0.05) or ** (p ≤ 0.01). Along with pathways which describe general processes of the cell, we identified several immune system-specific pathways (A) and several pathways which are specific to certain diseases (B). P-values indicate the probability of random association between the genes in the data set and the canonical pathway. Abbreviations used in the figure: C-CR interaction = cytokine–cytokine receptor interaction; Transcr. misreg. in cancer = transcriptional misregulation in cancer.

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Virology Journal

ISSN: 1743-422X