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Table 2 Qualitative comparison between PPRNT and FFRNT

From: Pseudo-plaque reduction neutralization test (PPRNT) for the measurement of neutralizing antibodies to Crimean-Congo hemorrhagic fever virus

 

FFRNT

Sensitivity (%)

Specificity (%)

Agreement (%)

Kappa

 

> 4

< 4

*(95% CI)

(95% CI)

(95% CI)

 

PPRNT

      

> 4

49

1

98.0

100

96.6

0.96

< 4

0

20

    
  1. *Fold differences were calculated based on the within and between assay standard deviation of log10 titres within which results from testing a sample twice should fall 95% of the time.