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Table 2 Distributation of HBVrt mutations among the three genotypes

From: Characterization of antiviral resistance mutations among the Eastern Indian Hepatitis B virus infected population

 

Antiviral treated (N= 30)

Treatment naïve (N= 55)

GENOTYPES→

HBV/A (4)

HBV/C (10)

HBV/D (16)

HBV/A (22)

HBV/C (13)

HBV/D (20)

Putative NAr mutation

Y126H (4), N139E/Q (4), F221Y(4)

I91L (9), Y126H (10), W153R (10),

I91L (15), Y126H (11) Y126R (5), W153R (16), S213T (1), Q215S (1), Q215P (1),

Y126H (17), N139E (1), N139Q (21), V191I (1), F221Y (22),

I91L(12), Y126H (13), W153R (13), V191F (1), Q215E (1),

I91L (20), Y126R (13), Y126H (7), T128I (1), W153R (20), Q215H (1), Q215S (1), F221Y (1), L229F (1)

Pretreatment mutation

N139E/Q (4), I224V (4)

 

Y124H (15), I224V (16)

Y124D (1), Y124N (21), N139E (1), N139Q (21), I224V (22)

Y124H (1), D134E(3), I224V (1)

Y124H (19), Y124N(1), D134E(1), I224V(20)

  1. Values in the parentheses indicates number of isolates.