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Table 3 Univariate analysis of risk factors for CMV DNA positive in patients with inflammatory bowel disease

From: The prevalence and risk factors of cytomegalovirus infection in inflammatory bowel disease in Wuhan, Central China

 

CMV DNA+/DNA-

 

UC

CD

 

(161/28)

(29/8)

Age

Number

P value

OR (95% CI)

Number

P value

OR (95% CI)

 ≤50 ys

117/22

0.514

0.725 (0.276 ~ 1.907)

18/6

0.685

0.545 (0.093 ~ 3.194)

 >50 ys

44/6

  

11/2

  

Sex

      

 male

95/14

0.373

1.439 (0.644 ~ 3.218)

19/4

0.445

1.900 (0.390 ~ 9.256)

 female

66/14

  

10/4

  

Smoking

      

 yes

40/5

0.423

1.521 (0.542 ~ 4.264)

7/2

1.000

0.840 (0.138 ~ 5.115)

 no

121/23

  

25/6

  

Drinking

      

 Yes

62/13

0.429

0.723 (0.322 ~ 1.621)

9/3

0.403

0.500 (0.100 ~ 2.510)

 no

99/15

  

30/5

  

Diet composition

      

 vegetarian food

15/3

1.000

0.856 (0.231 ~ 3.174)

3/3

0.101

0.192 (0.030 ~ 1.241)

 mixed food

146/25

  

26/5

  

Fever

      

 yes

30/2

0.221

2.977(0.670 ~ 13.235)

4/0

0.557

N/A

 no

131/26

  

25/8

  

Hemoglobin(G/L)

      

 ≤70

8/1

1.000

1.412 (0.170 ~ 11.747)

0/0

-

N/A

 >70

153/27

  

29/8

  

Albumin(G/L)

      

 ≤35

18/3

1.000

1.049 (0.288 ~ 3.826)

11/2

0.685

1.833 (0.313 ~ 10.735)

 >35

143/25

  

18/6

  

Disease severity

      

 mild and moderate

140/28

0.048*

N/A

24/6

0.631

1.600 (0.247 ~ 10.360)

 severe

21/0

  

5/2

  

Location

      

 distal colitis

123/17

0.080

2.094 (0.903 ~ 4.857)

   

 pancolitis

38/11

     

 ileal

   

7/1

0.734

N/A

 Colonic

   

11/3

  

 ileocolon

   

11/4

  

Treatment

      

ASA/SASP

131/18

0.041*

2.426 (1.017 ~ 5.784)

19/1

0.014*

13.300 (1.429 ~ 123.790)

corticosteroids

45/2

0.035*

5.043 (1.149 ~ 22.128)

8/0

0.160

N/A

immunosuppressant

5/0

1.000

N/A

2/0

1.000

N/A

  1. CMV, cytomegalovirus; UC, ulcerative colitis; ASA, aminosalicylic acid; SASP, salicylazosulfapyridine.
  2. *indicate significant difference.