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Table 3 Univariate analysis of risk factors for CMV DNA positive in patients with inflammatory bowel disease

From: The prevalence and risk factors of cytomegalovirus infection in inflammatory bowel disease in Wuhan, Central China

  CMV DNA+/DNA-
  UC CD
  (161/28) (29/8)
Age Number P value OR (95% CI) Number P value OR (95% CI)
 ≤50 ys 117/22 0.514 0.725 (0.276 ~ 1.907) 18/6 0.685 0.545 (0.093 ~ 3.194)
 >50 ys 44/6    11/2   
Sex       
 male 95/14 0.373 1.439 (0.644 ~ 3.218) 19/4 0.445 1.900 (0.390 ~ 9.256)
 female 66/14    10/4   
Smoking       
 yes 40/5 0.423 1.521 (0.542 ~ 4.264) 7/2 1.000 0.840 (0.138 ~ 5.115)
 no 121/23    25/6   
Drinking       
 Yes 62/13 0.429 0.723 (0.322 ~ 1.621) 9/3 0.403 0.500 (0.100 ~ 2.510)
 no 99/15    30/5   
Diet composition       
 vegetarian food 15/3 1.000 0.856 (0.231 ~ 3.174) 3/3 0.101 0.192 (0.030 ~ 1.241)
 mixed food 146/25    26/5   
Fever       
 yes 30/2 0.221 2.977(0.670 ~ 13.235) 4/0 0.557 N/A
 no 131/26    25/8   
Hemoglobin(G/L)       
 ≤70 8/1 1.000 1.412 (0.170 ~ 11.747) 0/0 - N/A
 >70 153/27    29/8   
Albumin(G/L)       
 ≤35 18/3 1.000 1.049 (0.288 ~ 3.826) 11/2 0.685 1.833 (0.313 ~ 10.735)
 >35 143/25    18/6   
Disease severity       
 mild and moderate 140/28 0.048* N/A 24/6 0.631 1.600 (0.247 ~ 10.360)
 severe 21/0    5/2   
Location       
 distal colitis 123/17 0.080 2.094 (0.903 ~ 4.857)    
 pancolitis 38/11      
 ileal     7/1 0.734 N/A
 Colonic     11/3   
 ileocolon     11/4   
Treatment       
ASA/SASP 131/18 0.041* 2.426 (1.017 ~ 5.784) 19/1 0.014* 13.300 (1.429 ~ 123.790)
corticosteroids 45/2 0.035* 5.043 (1.149 ~ 22.128) 8/0 0.160 N/A
immunosuppressant 5/0 1.000 N/A 2/0 1.000 N/A
  1. CMV, cytomegalovirus; UC, ulcerative colitis; ASA, aminosalicylic acid; SASP, salicylazosulfapyridine.
  2. *indicate significant difference.