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Figure 4 | Virology Journal

Figure 4

From: A novel DNA vaccine expressing the Ag85A-HA2 fusion protein provides protection against influenza A virus and Staphylococcus aureus

Figure 4

Cytokine levels in mouse lung homogenates. IFN-γ (*P < 0.05) (A) and IL-10 (*P < 0.05) (B) of lung homogenates day 8 after infection with A/PR/8/34 and on day 2 after infection with S. aureus. The pulmonary IFN-γ levels of mice vaccinated with pEGFP/Ag85A-HA2 were significantly higher than those vaccinated with pEGFP/HA2 on day 8 after infection with A/PR/8/34 (P < 0.05). The pulmonary IFN-γ levels of mice vaccinated with pEGFP/HA2 were significantly higher than those vaccinated with pEGFP-C2 or PBS (P < 0.05). The pulmonary levels of the anti-inflammatory cytokine IL-10 were significantly higher in the PBS group and the pEGFP-C2 vaccinated group than those in the other groups at day 2 after infection with S. aureus (P < 0.05).

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