Geographical distribution of low pathogenic ISAV (ISAV-HPR0) cases and ISA outbreaks from May 2011 to April 2013 in X, XI and XII Regions of Chile. (A) ISAV-HPR0 and ISA outbreaks in X and XI Regions. The black dots correspond to ISAV-HPR0 positive farm sites. The red dots correspond to the two 2013 ISA outbreaks in XI Region. The red circle indicates the space-time cluster identified from the space-time permutation scan test. (B) ISAV-HPR0 in XII Region. The black dots correspond to ISAV-HPR0 positive farm sites.