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Table 2 Amino acid substitution in the variable region and neutralizing epitopes of the F-gene sequences of the Japanese field strains

From: Molecular epidemiology of Newcastle disease virus isolates from vaccinated commercial poultry farms in non-epidemic areas of Japan

Ā 

Hypervariable region

Neutralizing epitopes

Virus

4

10

11

13

20

21

27

52

63

78

93

101

121

72

74

75

78

79

157-171

343

Consensusa

K

P

A

L

M

L

C

I

V

K

T

R

V

D

E

A

K

A

SIAATNEAVHEVT

L

JP/Osaka/2440/1969

-b

-

V

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

JP/Ibaraki/SM87/1987

-

L

V

P

T

-

-

-

I

-

S

-

I

-

-

-

-

-

-

-

JP/Ibaraki/SG106/1999

I

-

-

-

-

P

R

V

-

R

-

K

-

-

-

-

R

-

-

-

JP/Chiba/BY103/2001

I

-

-

-

-

P

R

V

-

R

-

K

-

-

-

-

R

-

-

-

JP/Ibaraki/IS5/2002

I

-

-

-

-

P

R

V

-

R

-

K

-

-

-

-

R

-

-

-

JP/Ibaraki/IS2/2002

I

-

-

-

-

P

R

V

-

R

-

K

-

-

-

-

R

-

-

-

JP/Miyagi/AGT/2002

I

-

-

-

-

P

R

V

-

R

-

K

-

-

-

-

R

-

-

-

JP/Chiba/BY7/2002

I

-

-

-

-

P

R

V

-

R

-

K

-

-

-

-

R

-

-

-

JP/Fukushima/NYF3/2002

I

-

-

-

-

P

R

V

-

R

-

K

-

-

-

-

R

-

-

-

JP/Sato/30

R

-

-

-

A

-

H

-

-

-

-

-

I

-

-

-

-

-

n.d.

n.d.

US/B1/47

R

-

-

M

A

-

-

-

-

-

-

-

I

-

-

-

-

-

-

-

LaSota/46

R

-

-

M

A

-

-

-

-

-

-

-

I

-

-

-

-

-

-

-

JP/Ishii/62

R

-

V

-

V

-

-

-

-

-

-

-

I

-

-

-

-

-

-

-

  1. aThe consensus amino acid sequence was derived from 100ā€“180 velogenic, mesogenic and lentogenic NDV strains from GenBank; bSame as consensus sequence.