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Table 2 List of all 17 down regulated genes and their functions

From: Transcriptional profiling of feline infectious peritonitis virus infection in CRFK cells and in PBMCs from FIP diagnosed cats

No.

Fold change

BLAST result

Accession number

Gene Pproduct punction

01

-2.04

JAG1

NG_ 007496

TLRs response, positive regulation of Notch signaling pathway

02

-2.04

c-KIT

NM_ 001009837

signal transduction, apoptosis inducer, clathrin dependent endocytosis

03**

-2.14/ -2.44

JUB

XM_ 537368

co-trancriptional repressor with GFI-1, cell adhesion

04

-2.22

SERPINB1

AF 053630

neutrophil proteolytic activity inhibitor,

05

-2.34

CD59

NM_ 001112709

T-cell differentiation, gene transcription repression

06

-2.40

COTL1

XM_ 001144958

pro-inflammatory leukotrienes activation

07**

-2.62/ -2.71

RASL11B

XM_ 848847

macrophage activation

08

-2.73

DUSP1

XM_ 002916919

regulate cytokine expression, attract phagocytic cell to inflammation site

09

-2.84

RAB8A

XM_ 002912702

protein localization & transport, exocytosis

10

-3.22

RPL30

AB 070559

RNA translation

11

-3.23

UBTD2

XM_ 546238

anti-apoptotic activity

12

-3.27

CKS2

AF 506708

anti-apoptotic activity

13

-4.80

SRP9

XM_ 849646

protein export

14*

-4.98/ -5.89

CRIP1

XM_ 850438

T helper cytokines regulation, immune cells differentiation and proliferation

15

-10.04

ID1

XM_ 847117

anti-apoptotic activity, TGF-beta signaling pathway

16

-∞

RNF7

XM_ 003433156

anti-apoptotic activity

17

-∞

RPL39

NG_ 016250

RNA translation

  1. # dash symbol (-) represents down regulation of genes in order to differentiate with fold change values of up regulated genes.
  2. **Two transcripts from the same gene with similar E-value, score and gaps.