Table 2 Comparasion of mutated sites in pDEV-vac (KF693236), the published DEV vaccine sequence (KF487736)), and four viruses DEV-vac, rDEV, rDEV-BAC and rDEV-Cre
Modification (nt position, according to KF487736) | pDEV-vac (GenBank: KF693236) | Reference strain (GenBank: KF487736) | DEV-vac | rDEV | rDEV-BAC | rDEV-Cre |
|---|---|---|---|---|---|---|
41 128 | A | G | G | A | A | A |
43 596 | A | C | C | A | A | A |
75 096 | A | G | G | A | A | A |
110 795 | C | T | T | C | C | C |
59 643 | T | C | T | T | T | T |
| Â | Deletion 80 NT: | GGGTTCCAAAGG | GGGTTCCAAAGG | GGGTTCCAAAGG | Deletion 80 NT: | Deletion 80 NT: |
|  | — — — — — — — — | TTTTACGGTATTA | TTTTACGGTATT | TTTTACGGTATT | — — — — — — — — | — — — — — — — — |
|  | — — — — — — — — | GGGTTAGGGTTG | AGGGTTAGGGTT | AGGGTTAGGGTT | — — — — — — — — | — — — — — — — — |
119 773–119 852 | — — — — — — — — | GCAGGGTTCCAA | GGCAGGGTTCCA | GGCAGGGTTCCA | — — — — — — — — | — — — — — — — — |
|  | — — — | AGGTTTTACGGT | AAGGTTTTACGG | AAGGTTTTACGG | — — — | — — — |
| Â | Â | ATTAGGGTTAGG | TATTAGGGTTAG | TATTAGGGTTAG | Â | Â |
| Â | Â | GTTGGCA | GGTTGGCA | GGTTGGCA | Â | Â |
129 421–129 422 | Insertion: AA | – | – | A- | AA | AA |
143 005 | T | G | T | T | T | T |
147 986–147 987 | Insertion: TT | – | – | T- | TT | TT |
| Â | Deletion 80 nt: | CCTAATACCGTA | CCTAATACCGTA | Deletion 40 nt: | Deletion 80 nt: | Deletion 80 nt: |
AAACCTTTGGAA | AAACCTTTGGAA | |||||
|  | — — — — — — — — | CCCTGCCAACCC | CCCTGCCAACCC | CCTAATACCGTA | — — — — — — — — | — — — – – – – |
AAACCTTTGGAA | — — — — — — — — | — — — – – – – | ||||
CCCTGCCAACCC | — — — – – – – | — — — – – – – | ||||
TAAC — — — — — — — — — | — — — | — — — | ||||
157 498–157 877 | — — — — — — — — | TAACCCTAATAC | TAACCCTAATAC |  |  |  |
|  | — — — — — — — — | CGTAAAACCTTT | CGTAAAACCTTT |  |  |  |
|  | — — — | GGAACCCTGCCA | GGAACCCTGCCA | — — — — — — — — |  |  |
| Â | Â | ACCCTAAC | ACCCTAAC | Â | Â | Â |
158 090 | Insertion : G | - | G | G | G | G |