Horizontal acquisition and a broad biodistribution typify simian foamy virus infection in a cohort of Macaca fascicularis

Table 2 Tissues infected by SFV

			Proviral load in tissues (copies/15000 cells)
Macaque	Age (years)	Total	Kidney	Tongue	PLN	MLN	Lung	Liver	Salivary gland	Spleen	Large intestine	Small intestine	SGLN
M955C	0.5	1.00				0.50							0.50
958EH	1
956ED	2	6.21	0.50			0.50		3.21	0.50		0.50	0.50	0.50
M126	7	14.60	0.50	3.60		2.42	1.00	0.50	0.50	2.00	0.50	3.59
963DBE	10	263.11	2.94	0.50	18.56	34.29	3.82	28.60	5.24	12.45	130.39		26.33
979B	12	150.94	10.56	21.59	1.13	2.27	6.59	4.99	0.50	6.51	37.47	59.32
176ABA	13	56.83		3.98		49.86				3.00
024L	14	6.47	3.52		0.50	0.38		0.50	0.50	1.08
604F	14	118.90	0.50	58.36	13.08	7.20	8.19	0.39	1.16	3.82	14.27	11.45	0.50
088AD	15	39.05	2.31			1.96		9.65	1.25	6.80	2.57	14.51
604E	15	26.45	0.63		0.50	1.19	1.02	12.31		6.89	1.16	2.75
768E	15	44.68	8.66				11.84	1.63	0.29	9.91	11.65	0.21	0.50
017K	16	24.92	1.84	4.49			0.50	1.00	1.13	4.90	10.56		0.50
184E	17	84.23	5.06	41.86	2.24		1.28	3.64	0.57	3.19		26.39
654D	17	150.63	6.31	55.18	55.79		10.64	2.95	2.74		9.42	7.60
820A	18	58.78	0.53	45.25		0.50	0.50	0.50	0.85	0.50	9.04	0.50	0.61
085E	18	366.32	7.11	38.87	14.06	4.67	6.16	6.55	2.86	2.37	24.80	258.36	0.50
768B*	20	ND	+			+	+	+	+	+		+	+

The tissues identified as SFV infected by Pol PCR in cynomolgus macaques are presented. PLN, peripheral lymph node; MLN, mesenteric lymph node; SGLN, salivary gland-associated lymph node; *, quantified proviral loads not available for 768B; ND, not determined.

ISSN: 1743-422X