Table 2 Clade-specific amino acid variation
From: Analysis of whole genome sequences of 16 strains of rubella virus from the United States, 1961–2009
aa position | Clade 1 | Clade 2 | Gene (Domain) | Reference* | |
|---|---|---|---|---|---|
(n = 20) | (n = 10) | ||||
NSP | 464 | R | H | P150 (unknown) | |
551 | A | T | P150 (Q domain) | [14] | |
725 | G | D | P150 (HVR) | [10] | |
859 | T | A | P150 (X) | [9] | |
864 | A | E/D | P150 (X) | [9] | |
1064 | S | G | P150 (Protease) | [15] | |
1082 | T | A | P150 (Protease) | [15] | |
1147 | L | R/Q | P150 (Protease) | [15] | |
SP | 116 | S | T | C (unknown) | |
308 | M | I/L | E2 (antigenicity) | [16] | |
323 | Q | K | E2 (antigenicity) | [16] | |
420 | A/V | T | E2 (unknown) | ||
700 | E | D | E1 (unknown) |