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Table 3 Pro-inflammatory cytokines secretion by vaginal keratinocytes after treatment for 24 h with extracts/n-butanol fraction prepared from stem bark of A. catechu

From: Extracts from Acacia catechu suppress HIV-1 replication by inhibiting the activities of the viral protease and Tat

Treatment with plant extract/fraction* Level of cytokines (pg/ml)  
IL-8 IL-1β IL-6 TNF
Control 282 ± 5.3 2.2 ± 0.2 118 ± 9.1 1.1 ± 0.6
Aqueous extract 248 ± 11.1 3.4 ± 0.2 115.0 ± 8.4 1.7 ± 0.1
50% Ethanolic extract 40.4 ± 3.9** 4.0 ± 0.0 34.8 ± 1.3# 1.7 ± 0.3
n-Butanol fraction 2.7 ± 0.6** 3.4 ± 0.3 8.8 ± 0.6# 1.8 ± 0.5
  1. *Various plant extracts/n-butanol fraction were used at 100 μg/ml.
  2. **p < 0.001 as compared to IL-8 concentration in the control group.
  3. #p < 0.001 as compared to IL-6 concentration in the control group.
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