Figure 3From: A recombinant pseudotyped lentivirus expressing the envelope glycoprotein of Hantaan virus induced protective immunity in miceFrequency of antigen-specific IL-10- or IL-4-secreting T cells in splenocytes of immunized mice (n=4). Number of GPspecific IL-4-secreting T cells (A) and IL-10-secreting T cells (B) were evaluated using ELISPOT assays. Results are shown as the mean value of the number of spots observed for 106 spleen cells, obtained from triplicate wells. The rLV-M induced effective IL-10 and IL-4 responses, which were higher than the rLV-ZsGreen control and NS group (*p<0.05), and equivalent to the inactivated vaccine group.Back to article page