Skip to main content

Table 1 Th polarization

From: The effects of HIV Tat DNA on regulating the immune response of HIV DNA vaccine in mice

  pGag (titer) pGag + pTat (titer) Blank (titer)
IgG1 (Th2) 300 300 50 (negative)
IgG2a (Th1) 50 (negative) 350 50 (negative)
Th1:Th2 index 0.17 1.17 --
  pEnv (titer) pEnv + pTat (titer) Blank (titer)
IgG1 (Th2) 600 750 50 (negative)
IgG2a (Th1) 650 750 50 (negative)
Th1:Th2 index 1.08 1 --
  pPol (titer) pPol + pTat (titer) Blank (titer)
IgG1 (Th2) 200 200 50 (negative)
IgG2a (Th1) 50 (negative) 400 50 (negative)
Th1:Th2 index 0.25 2 --
  1. The mean value of each group of mice (the same data as showed in Figure 4B) was showed in this table, and used to calculate the index of IgG2a/IgG1 [26]. Th-polarization response in mice was determined according to the value of IgG2a/IgG1 [27, 28]. The value of Th1:Th2 are accurate to two decimal places. All experiments were repeated once, and the results were consistent.