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Figure 2 | Virology Journal

Figure 2

From: Differential cellular gene expression in duck trachea infected with a highly or low pathogenic H5N1 avian influenza virus

Figure 2

Plots of sequences differentially expressed in duck trachea after H5N1 infection using the significance analysis micro-array software. A and B: One-class analyses of microarray data were performed for each dataset: after LPAI-H5N1 (A) or HPAI-H5N1 (B) at 4 h (left panels) or 8 h (right panels) post-infection, as compared to mock-infected. The false discovery rate was set at 4.76 (A, left panel), 4.81 (A, right panel), 5.7 (B, left panel) and 4.82% (B, right panel). C: Two-class analyses of microarray data were performed for each time post-infection: at 4 h (right panel) or 8 h (left panel) post-infection by comparing HPAI-H5N1 infection to LPAI-H5N1 infection. The false discovery rate was set at 0 (C, right panel) and 4.15% (C, left panel). The x-axis values represent expected expression and the y-axis represent observed expression. Parallel lines represent the threshold with the corresponding false discovery rate set. Black dots represent sequences not differentially expressed between the two compared conditions. Red dots and red numbers represent significant up-regulated sequences in HPAI- or LPAI-infected tracheas as compared to mock-infected (A, B), or HPAI-infected tracheas as compared to LPAI-infected tracheas (C). Green dots and numbers represent significant down-regulated sequences in HPAI- or LPAI-infected tracheas as compared to mock-infected (A, B), or HPAI-infected tracheas as compared to LPAI-infected tracheas (C).

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