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Table 3 Virus recovery from organ tissues of ferrets

From: Rapid emergence of a virulent PB2 E627K variant during adaptation of highly pathogenic avian influenza H7N7 virus to mice

  

Virus titers in organs collected from ferrets on day 5 p.i.a

Virus

Ferret

NTb

Tr

L1c

L2

L3

L4

Ileum

Jejun

Kidney

Liver

Spleen

Heart

Brain

chH7N7

#1

4.1

4.3

2.4

5.0

2.4

2.6

−

−

−

−

−

−

−

 

#2

nd

3.7

2.4

2.4

2.4

4.9

−

−

−

−

−

−

2.5

 

#3

3.2

2.7

4.8

4.7

2.4

3.2

−

−

−

−

−

−

−

maH7N7

#1

5.6

5.1

3.8

4.4

5.2

4.0

−

−

−

−

−

−

−

 

#2

3.4

5.7

6.3

6.3

6.3

6.8

3.0

3.4

−

2.5

−

2.7

3.0

 

#3

3.2

5.7

6.2

7.0

7.4

5.9

2.7

−

2.5

−

2.6

3.0

−

  1. aVirus titers expressed as log10 TCID50 per gram tissue.
  2. bNT = nasal turbinate; Tr = trachea; Jejun = jejunum.
  3. cLung tissues were sampled from left cranial (L1), right cranial (L2), left caudal (L3) and right caudal (L4) lobes.
  4. nd = not determined; − = <2.4 log10 TCID50/g.