Skip to main content

Advertisement

Table 3 Metabolic changes in HIV-infected patients with hypertriglyceridemia: comparsion with HIV/HCV co-infected patients and normal control participants

From: Liver steatosis in Chinese HIV-infected patients with hypertriglyceridemia: characteristics and independent risk factors

Characteristics Control HIV/HCV co-infection HIV-infected patients with hypertriglyceridemia p value
Age (yr) 42.0 ± 4.3 42.7 ± 6.1 42.9 ± 9.3 0.873
Male (%) 14 (46.7%) 47 (68.1%) 109 (66.9%) 0.104
Female (%) 16 (53.3%) 22 (31.9%) 54 (33.1%)
Transmission route     
Former plasma donators -- 14 (20.3%) 41 (25.2%) --
Blood transfusion -- 39 (59.5%) 9 (5.5%) --
Intravenous drug users -- 7 (7.2%) 20 (12.3%) --
Sexual transmission -- 9 (13.0%) 89 (54.6%) --
Unknown reason -- 0 (0.0%) 4 (2.5%) --
Biochemistry tests     
ALT (U/L) 18.7 ± 10.9 44.3 ± 40.3 32.5 ± 29.3 0.001
T-BIL (umol/L) 11.1 ± 3.9 12.7 ± 9.2 11.4 ± 6.2 0.129
BUN (mmol/L) 4.7 ± 1.1 4.8 ± 3.9 4.9 ± 1.4 0.836
FPG (mmol/L) 5.5 ± 1.0 5.7 ± 1.7 5.7 ± 1.8 0.755
Blood lipid levels     
TG (mmol/L) 1.9 ± 1.7 1.8 ± 1.1 5.7 ± 5.2 <0.001
TC (mmol/L) 4.9 ± 0.9 3.7 ± 1.1 5.5 ± 1.7 <0.001
LDL (mmol/L) 2.8 ± 0.7 2.2 ± 0.9 2.8 ± 1.0 <0.001
HDL (mmol/L) 1.4 ± 0.7 0.9 ± 0.4 1.2 ± 0.3 <0.001
TG ≥2.26 mmol/L (%) 4 (13.3%) 12 (17.4%) 163 (100%) <0.001
1.70 ≤ TG ≤ 2.25 mmol/L 6 (20.0%) 11 (15.9%) 0 (0%)
TC ≥6.22 mmol/L 2 (6.7%) 2 (2.9%) 45 (27.6%) <0.001
5.18 ≤ TC ≤ 6.19 mmol/L 10 (33.3%) 2 (2.9%) 39 (23.9%)
LDL ≥4.14 mmol/L 0 (0.0%) 2 (2.9%) 14 (8.6%) 0.041
3.37 ≤ LDL ≤ 4.14 mmol/L 7 (23.3%) 5 (7.2%) 24 (14.7%)
HDL ≤ 1.04 mmol/L 7 (23.3%) 50 (72.4%) 34 (20.9%) <0.001
Metabolic sydrome 5 (16.7%) 13 (18.9%) 78 (47.9%) <0.001
Liver steatosis 5 (16.7%) 14 (20.3%) 75 (46%) <0.001
  1. Note: Across study sites, 180 HIV-infected Patients with Hypertriglyceridemia were recruited and scheduled for ultrasound imaging. As 17 did not appear for the screening visit, data were available for 163 participants.