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Table 3 Metabolic changes in HIV-infected patients with hypertriglyceridemia: comparsion with HIV/HCV co-infected patients and normal control participants

From: Liver steatosis in Chinese HIV-infected patients with hypertriglyceridemia: characteristics and independent risk factors

Characteristics

Control

HIV/HCV co-infection

HIV-infected patients with hypertriglyceridemia

p value

Age (yr)

42.0 ± 4.3

42.7 ± 6.1

42.9 ± 9.3

0.873

Male (%)

14 (46.7%)

47 (68.1%)

109 (66.9%)

0.104

Female (%)

16 (53.3%)

22 (31.9%)

54 (33.1%)

Transmission route

    

Former plasma donators

--

14 (20.3%)

41 (25.2%)

--

Blood transfusion

--

39 (59.5%)

9 (5.5%)

--

Intravenous drug users

--

7 (7.2%)

20 (12.3%)

--

Sexual transmission

--

9 (13.0%)

89 (54.6%)

--

Unknown reason

--

0 (0.0%)

4 (2.5%)

--

Biochemistry tests

    

ALT (U/L)

18.7 ± 10.9

44.3 ± 40.3

32.5 ± 29.3

0.001

T-BIL (umol/L)

11.1 ± 3.9

12.7 ± 9.2

11.4 ± 6.2

0.129

BUN (mmol/L)

4.7 ± 1.1

4.8 ± 3.9

4.9 ± 1.4

0.836

FPG (mmol/L)

5.5 ± 1.0

5.7 ± 1.7

5.7 ± 1.8

0.755

Blood lipid levels

    

TG (mmol/L)

1.9 ± 1.7

1.8 ± 1.1

5.7 ± 5.2

<0.001

TC (mmol/L)

4.9 ± 0.9

3.7 ± 1.1

5.5 ± 1.7

<0.001

LDL (mmol/L)

2.8 ± 0.7

2.2 ± 0.9

2.8 ± 1.0

<0.001

HDL (mmol/L)

1.4 ± 0.7

0.9 ± 0.4

1.2 ± 0.3

<0.001

TG ≥2.26 mmol/L (%)

4 (13.3%)

12 (17.4%)

163 (100%)

<0.001

1.70 ≤ TG ≤ 2.25 mmol/L

6 (20.0%)

11 (15.9%)

0 (0%)

TC ≥6.22 mmol/L

2 (6.7%)

2 (2.9%)

45 (27.6%)

<0.001

5.18 ≤ TC ≤ 6.19 mmol/L

10 (33.3%)

2 (2.9%)

39 (23.9%)

LDL ≥4.14 mmol/L

0 (0.0%)

2 (2.9%)

14 (8.6%)

0.041

3.37 ≤ LDL ≤ 4.14 mmol/L

7 (23.3%)

5 (7.2%)

24 (14.7%)

HDL ≤ 1.04 mmol/L

7 (23.3%)

50 (72.4%)

34 (20.9%)

<0.001

Metabolic sydrome

5 (16.7%)

13 (18.9%)

78 (47.9%)

<0.001

Liver steatosis

5 (16.7%)

14 (20.3%)

75 (46%)

<0.001

  1. Note: Across study sites, 180 HIV-infected Patients with Hypertriglyceridemia were recruited and scheduled for ultrasound imaging. As 17 did not appear for the screening visit, data were available for 163 participants.