Table 2 Characteristics and independent risk factors of liver steatosis in Chinese HIV patients with hypertriglyceridemia analyzed with univariate and multivariate regression analysis

Features

Age (yr)

42.9 ± 9.3

43.2 ± 9.5

42.9 ± 9.2

0.79

Male

109 (66.9%)

52 (31.9%)

57 (35.0%)

0.02

Female

54 (33.1%)

36 (22.1%)

18 (11.0%)

Smoking histroy

52 (31.9%)

27 (30.7%)

25 (33.3%)

0.72

Drinking

17 (10.4%)

12 (13.6%)

5 (6.7%)

0.03

BMI (Kg/m ² )

Male patients

25-29.9

76 (69.7%)

41 (37.6%)

35 (32.1%)

0.71

≥30

13 (11.9%)

6 (5.5%)

7 (6.4%)

18.6-24.9

20 (18.4)

11 (10.1%)

9 (8.3%)

Female patients

25-29.9

36 (66.7%)

12 (22.2%)

24 (44.5%)

1.00

≥30

6 (11.1%)

2 (3.7%)

4 (7.4%)

18.6-24.9

12 (22.2%)

4 (7.4%)

8 (14.8%)

Biochemistry tests

ALT (U/L)

32.5 ± 29.3

28.8 ± 25.7

36.7 ± 32.7

0.11

AST (U/L)

31.7 ± 30.9

37.7 ± 32.1

31.3 ± 21.5

0.78

CK

115 ± 112

131 ± 186

109 ± 62

0.44

BUN (mmol/L)

4.9 ± 1.4

4.8 ± 1.0

4.9 ± 1.8

0.55

Cr (umol/L)

77.0 ± 28.5

82.3 ± 18.7

70.9 ± 35.9

0.01

Blood lipid levels

TG (mmol/L)

5.7 ± 5.2

4.7 ± 3.8

6.9 ± 6.3

0.012

0.026

TC (mmol/L)

5.5 ± 1.7

5.3 ± 1.7

5.8 ± 1.7

0.07

LDL (mmol/L)

2.8 ± 1.0

2.9 ± 0.9

2.7 ± 1.1

0.31

HDL (mmol/L)

1.3 ± 0.3

1.3 ± 0.3

1.2 ± 0.4

0.08

FPG (mmol/L)

5.7 ± 1.8

5.1 ± 1.2

6.5 ± 2.1

<0.001

Metabolic sydrome

78 (47.9%)

34 (38.6%)

44 (58.7%)

0.01

0.024

HIV infection

Time since HIV

132 ± 73

141 ± 74

117 ± 69.5

0.07

diagnosis (M)

Mos. on ART (M)

38.7 ± 25.3

37.5 ± 25.3

40.1 ± 25.5

0.39

Current CD4

316 ± 191

240 ± 141

401 ± 204

<0.001