Skip to main content

Advertisement

Table 2 Characteristics and independent risk factors of liver steatosis in Chinese HIV patients with hypertriglyceridemia analyzed with univariate and multivariate regression analysis

From: Liver steatosis in Chinese HIV-infected patients with hypertriglyceridemia: characteristics and independent risk factors

     Univariate analysis Mutivariate analysis
Charateristics All patients Liver steatosis Non-steatosis OR P value OR P value
Features        
Age (yr) 42.9 ± 9.3 43.2 ± 9.5 42.9 ± 9.2 0.99 0.79   
Male 109 (66.9%) 52 (31.9%) 57 (35.0%) 0.47 0.02   
Female 54 (33.1%) 36 (22.1%) 18 (11.0%)
Smoking histroy 52 (31.9%) 27 (30.7%) 25 (33.3%) 1.13 0.72   
Drinking 17 (10.4%) 12 (13.6%) 5 (6.7%) 4.615 0.03   
BMI (Kg/m 2 )        
Male patients        
25-29.9 76 (69.7%) 41 (37.6%) 35 (32.1%) 0.68 0.71   
≥30 13 (11.9%) 6 (5.5%) 7 (6.4%)     
18.6-24.9 20 (18.4) 11 (10.1%) 9 (8.3%)     
Female patients   
25-29.9 36 (66.7%) 12 (22.2%) 24 (44.5%) <0.001 1.00   
≥30 6 (11.1%) 2 (3.7%) 4 (7.4%)
18.6-24.9 12 (22.2%) 4 (7.4%) 8 (14.8%)
Biochemistry tests   
ALT (U/L) 32.5 ± 29.3 28.8 ± 25.7 36.7 ± 32.7 1.01 0.11   
AST (U/L) 31.7 ± 30.9 37.7 ± 32.1 31.3 ± 21.5 0.99 0.78   
CK 115 ± 112 131 ± 186 109 ± 62 0.99 0.44   
BUN (mmol/L) 4.9 ± 1.4 4.8 ± 1.0 4.9 ± 1.8 1.04 0.55   
Cr (umol/L) 77.0 ± 28.5 82.3 ± 18.7 70.9 ± 35.9 0.97 0.01   
Blood lipid levels   
TG (mmol/L) 5.7 ± 5.2 4.7 ± 3.8 6.9 ± 6.3 1.10 0.012 1.086 0.026
TC (mmol/L) 5.5 ± 1.7 5.3 ± 1.7 5.8 ± 1.7 1.19 0.07   
LDL (mmol/L) 2.8 ± 1.0 2.9 ± 0.9 2.7 ± 1.1 0.83 0.31   
HDL (mmol/L) 1.3 ± 0.3 1.3 ± 0.3 1.2 ± 0.4 0.37 0.08   
FPG (mmol/L) 5.7 ± 1.8 5.1 ± 1.2 6.5 ± 2.1 1.90 <0.001   
Metabolic sydrome 78 (47.9%) 34 (38.6%) 44 (58.7%) 2.25 0.01 2.092 0.024
HIV infection        
Time since HIV 132 ± 73 141 ± 74 117 ± 69.5 0.99 0.07   
diagnosis (M)        
Mos. on ART (M) 38.7 ± 25.3 37.5 ± 25.3 40.1 ± 25.5 1.00 0.39   
Current CD4 316 ± 191 240 ± 141 401 ± 204 1.01 <0.001   
  1. Notes: BMI body metabolic index, ALT Alanine aminotransferase, AST Aspartate aminotransferase, CK Creatine kinase, BUN Blood urea nitrogen, Cr Serum creatinine, TG triglyceride, TC Total cholesterol, LDL Low-density lipoprotein, HDL high-density lipoprotein, FPG Fasting plasma glucose.