Skip to main content

Table 3 Antiviral activities of ethanol extracts of T. sureni leaves (TSL), M. latifolia leaves (MLL), M. multiglandulosa stem (MMS) and F.fistulosa leaves (FFL) against various HCV strains of different genotypes

From: Antiviral activities of Indonesian medicinal plants in the East Java region against hepatitis C virus

HCV strain (genotype)

% Inhibitiona

T. sureni leaves

M. latifolia leaves

M. multiglandulosa stem

F. fistulosa leaves

(TSL)

(MLL)

(MMS)

(FFL)

J6/JFH1 P47 (2a)

97.2 ± 1.3b

98.0 ± 0.3

86.7 ± 1.4

93.8 ± 1.3

J6/JFH1 (2a)

98.5 ± 2.1

99.5 ± 0.7

73.2 ± 2.1

96.1 ± 1.4

JFH1 (2a)

100 ± 0.0

100.0 ± 0.0

67.3 ± 8.2

92.3 ± 0.0

H77C/JFH1 (1a)

98.2 ± 2.5

100.0 ± 0.0

83.9 ± 2.5

5.4 ± 2.5 c

J4/JFH1 (1b)

79.2 ± 11.8

91.7 ± 5.9

72.9 ± 8.8

93.8 ± 2.9

J8/JFH1 (2b)

100.0 ± 0.0

100.0 ± 0.0

34.4 ± 13.3 c

93.8 ± 0.0

S52/JFH1 (3a)

97.8 ± 3.1

100.0 ± 0.0

95.6 ± 3.1

97.8 ± 0.0

ED43/JFH1 (4a)

94.2 ± 1.2

98.3 ± 0.0

59.5 ± 1.2

97.5 ± 1.2

SA13/JFH1 (5a)

100.0 ± 0.0

96.1 ± 1.1

89.8 ± 1.1

93.8 ± 2.2

HK6a/JFH1 (6a)

100.0 ± 0.0

91.2 ± 4.2

67.6 ± 20.8

91.2 ± 4.2

QC69/JFH1 (7a)

100.0 ± 0.0

87.0 ± 6.1

39.1 ± 0.0 c

95.7 ± 6.1

  1. a% Inhibition at the concentration of 30 μg/ml.
  2. bData represent means ± SEM of data from two independent experiments using HCV J6/JFH1-P47.
  3. c% Inhibition of <40% are written in boldface letters.