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Table 2 Evolutionary characteristics of HBV genotypes based on the HBcAg gene using the uncorrelated log normal relaxed clock model produced by BEAST

From: An analysis of the molecular evolution of Hepatitis B viral genotypes A/B/D using a Bayesian evolutionary method

HBV genotype

Location, year reported

HBV TMRCA (years; 95% HPD)

Emergence time (year)

Substitution rate (CR)* 1.127 (0.925–1.329)

TMRCA(A)

Japan,1988 [20]

118 (54–194)

1894

TMRCA (B)

Japan,1988 [20]

184 (78–323)

1828

TMRCA (D)

Japan,1988 [20]

133 (65–230)

1879

  1. *Substitution rate are expressed as 10-3 substitutions per site per year.