Figure 4

Alignment of the RdRp conserved amino acid motifs of O. novo-ulmi encoded by mitochondrial viruses. Virus notations and labelling of the motifs follow Hong et al. [18]. Symbols shown below the alignment indicate identical amino acids (*), as well as higher (:) and lower (.) chemically-similar residues, respectively, as defined in the CLUSTAL W program. Analysis of the amino acid sequence of OnuMV1c showed at least three common motifs (shaded) that are typically conserved in the sequences of all polymerases showing RNA template specificity. Numbers in parentheses represent the number of amino acid residues between motifs.