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Figure 7 | Virology Journal

Figure 7

From: The N-end rule and retroviral infection: no effect on integrase

Figure 7

Intravirion processing of Gag and Gag-Pol polyproteins in HIV-1 integrase N-terminal mutants. WT and mutant HIV-1 virion particles were produced in the presence of varying concentrations of the HIV-1 protease inhibitor ritonavir and the cleavage pattern of the Gag and Gag Pol polypeptides were analyzed by immunoblot analysis. WT, methionine substituted (Met) and tryptophan substituted (Trp) integrase mutants were probed with antibodies to integrase (top) or p24 (bottom).

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