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Figure 5 | Virology Journal

Figure 5

From: Vascular leak ensues a vigorous proinflammatory cytokine response to Tacaribe arenavirus infection in AG129 mice

Figure 5

Evaluation of vascular permeability during TCRV infection in AG129 mice. TCRV- and sham-infected mice were infused with EBD on day 4, 7, 8, 9 and 10 of infection and systemic levels, as well as leakage into the viscera was evaluated. A) Individual mouse weights on day 0, 2, 4, 6, 8, 9, and 10 post-infection were determined and the data are presented as the group mean and standard deviation of the percent change in weight of surviving animals relative to their starting weights. B) Serum EBD levels and ratios of tissue to respective serum levels are shown for C) kidney, D), liver, E) lung, and F) spleen tissues. Day 9 data include values from two separate experiments. *P< 0.05, ** P< 0.01, *** P< 0.001 compared to sham-infected animals.

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