Figure 3

Histopathology in TCRV-infected AG129 mice at 9 days post-infection. Representative photomicrographs of liver A), lung C), and spleen (E) from AG129 mice sacrificed on day 9 post-infection with TCRV. Liver B), lung D), and spleen F) from control sham-infected mice. Hematoxylin and eosin staining shows A) multifocal moderate histiocytic, neutrophilic and lymphocytic hepatitis (400X), C) diffuse moderate interstitial pneumonia (400X), and E) white pulp hyperplasia (200X). For panels A-D, bar = 50 μm; for E and F, bar = 100 μm.