Table 3 Different chemokine’s levels of 44 patients in response to treatment

CXCL5(pg/ml)

Pretreatment

1.27500 ± .969563

1.33774 ± .792903

1.22044 ± 1.022862

1.42330 ± .925645

0.000^a, 0.602^b, 0.875^c, 0.770^d, 0.345^e, 0.703^f

12 Weeks

.71167 ± .459045

.90895 ± .588673

1.00456 ± .699765

.80800 ± .609552

24 Weeks

.7220 ± .46685

.9518 ± .57106

.7664 ± .43326

.8625 ± .63422

CXCL9(pg/ml)

Pretreatment

.19233 ± .114175

.20568 ± .076974

.18922 ± .074028

.18810 ± .063218

0.082^a, 0.744^b, 0.415^c, 0.962^d, 0.199^e, 0.517^f

12 Weeks

.19233 ± .124331

.14284 ± .040243

.16744 ± .127693

.12573 ± .053301

24 Weeks

.13750 ± .072116

.18945 ± .121548

.15544 ± .097306

.13464 ± .055773

CXCL11(pg/ml)

Pretreatment

.13520 ± .080444

.13945 ± .072608

.17885 ± .093798

.15742 ± .100730

0.187^a, 0.584^b, 0.459^c, 0.435^d, 0.065^e, 0.634^f

12 Weeks

.15260 ± .081185

.16190 ± .098519

.17154 ± .049891

.19991 ± .152004

24 Weeks

.14883 ± .038071

.17705 ± .102551

.12744 ± .044230

.19255 ± .161593

CXCL12(pg/ml)

Pretreatment

84.69483 ± 206.396544

.39289 ± .154332

.55400 ± .244147

.45300 ± .163781

0.117^a, 0.085^b, 0.085^c, 0.229^d, 0.065^e, 0.085^f

12 Weeks

.49400 ± .065023

.42263 ± .147961

.54833 ± .196068

.43490 ± .205439

24 Weeks

.373 ± .1015

.439 ± .1431

.496 ± .1217

.42900 ± .1590

CXCL13(pg/ml)

Pretreatment

.34000 ± .069974

.31553 ± .105584

.40567 ± .274538

.29844 ± .105315

0.002^a, 0.085^b, 0.085^c, 0.229^d, 0.065^e, 0.085^f

12 Weeks

.50483 ± .139194

.43342 ± .246432

.52944 ± .271026

.34133 ± .145816

24 Weeks

.47333 ± .181595

.53990 ± .377348

.62800 ± .455588

.39955 ± .128076

CXCL16(ng/ml)

Pretreatment

.94633 ± .101567

.87458 ± .244527

1.14611 ± .424545

1.01250 ± .331579

0.000^a, 0.221^b, 0.527^c, 0.689^d, 0.577^e, 0.866^f

12 Weeks

1.15333 ± .298719

1.11037 ± .323698

1.25411 ± .342009

1.24990 ± .417217

24 Weeks

1.26867 ± .353015

1.13953 ± .408803

1.29189 ± .354069

1.28820 ± .402766

E-cadherin(ng/ml)

Pretreatment

.41983 ± .425530

.40989 ± .436687

.82833 ± .843119

.68330 ± .660015

0.140^a, 0.274^b, 0.749^c, 0.504^d, 0.578^e, 0.794^f

12 Weeks

.72350 ± .666040

.55905 ± .577851

.92678 ± .782186

.74020 ± .657444

24 Weeks

.63783 ± .634553

.77832 ± .858560

.81578 ± .834449

.81032 ± .779431