Table 1 Clinical and Laboratory findings of the studied 57 chronic hepatitis C patients
From: Dynamic interplay between CXCL levels in chronic Hepatitis C patients treated by Interferon
Parameter | PEG-INTRON | PEGASYS | P-value |
|---|---|---|---|
I. Demographic features | N=32 | N=25 | |
-Age | 37.72 ± 8.44 | 42.28 ± 7.86 | 0.04 |
-BMI (Kg/m2) | 26.35 ± 4.06 | 27.87 ± 4.13 | 0.17 |
-Male | 27 (84.4%) | 21 (84%) | 0.96 |
-Female | 5 (15.6%) | 4 (16%) | |
-M:F ratio | 5.4:1 | 5.25:1 | |
II. Pathological features | |||
-Necro inflamm.activity; | A1 : 13 (40.6%) | A1 : 8 (32%) | 0.52 |
A2 : 10 (31.2%) | A2 : 10 (40%) | ||
A3 : 4 (12.5%) | A3 : 5 (20%) | ||
A4 : 2 (6.2%) | A4 : 1 (4%) | ||
-Fibrosis | Missed: 3 (9.3%) | Missed: 1 (4%) | |
F1: 17 (53.1%) | F1: 10 (40%) | 0.87 | |
F2 : 4 (12.5%) | F2 : 4 (16%) | ||
F3 : 4 (12.5%) | F3 : 3 (12%) | ||
F4 : 2 (6.2%) | F4 : 2 (8%) | ||
-Steatosis | Missed : 5(15.6%) | Missed : 6 (24%) | |
S0 : 11 (34.3%) | S0 : 11 (44%) | 0.53 | |
S1: 12 (37.5%) | S1: 12 (48%) | ||
S2: 7 (21.8%) | S2: 7 (28%) | ||
S3: 2 (6.2%) | S3: 2 (8%) | ||
III. Laboratory features | (Mean ± SD) | ||
HCV PCR Log (EQ/ML) | 5.4431 | 5.3824 | 0.79 |
(before treatment) | |||
WBC × 103/mm3 | 5.9344 ± 1.87266 | 6.1600 ± 2.55261 | 0.70 |
Hemoglobin (gm/dl) | 14.3 ± 1.5 | 12.1 ± 1.1 | 0.67 |
Platelets count/mm3 | 212148 ± 76965 | 150868.8 ± 1.0 | 0.32 |
AST (0-42 IU/L) | 60.1 ± 38.5 | 63.7200 ± 41.67 | 0.21 |
ALT (0-42 IU/L) | 72.6 ± 50.4 | 88.5 ± 48.6 | 0.31 |
ALP (0-290 IU/L) | 117.7 ± 67.7 | 93.9 ± 72.6 | 0.14 |
Total Bil(0.1-1.2 mg/dl) | 0.81 ± 0.41 | .7689 ± .311 | 0.81 |
Indirect Bil (mg/dl) | 0.45 ± 0.80 | .4526 ± 29238 | 0.69 |
Albumin (3.5-5.5gm/dl) | 4.21 ± 0.43 | 3.62 ± 0.32 | 0.34 |
Prothrombin (%) | 77.0 ± 27.0 | 71.1± 12.5 | 0.60 |
AFP (0-10 ng/ml) | 16.50 ± 9.76 | 10.1± 4.7 | 0.10 |