Figure 4

MP10 infection causes severe restrictive hypoventilation. Parameters reflecting respiratory functions, including (A) inspiratory time (TI), (B) respiratory frequency (F), and (C) minute volume (MV) of mock-infected and MP10-infected mice were recorded for 7 days (n = 20). Variations in body weight (D) were recorded for normalization. (●) Mock-infected group, (○) MP10-infected group (n = 12). E, the glucose levels in the blood of mock-infected and MP10-infected mice were detected at 6 d.p.i. (n = 24). * P < 0.05 and *** P < 0.001.