Table 1 Clinical presentations of two types of atypical HFMD
From: Atypical hand-foot-mouth disease in children: a hospital-based prospective cohort study
A typical HFMD (N=101) | Large vesicles (N=50) | Small rashes (N=51) | P value* | |
|---|---|---|---|---|
Demographics | ||||
Age (year) | 3.3 (± 3.8) | 4.0 (± 3.7) | 2.7 (± 1.8) | 0.12 |
Male | 65 (64%) | 35 (70%) | 30 (59%) | 0.004 |
Female | 36 (36%) | 15 (30%) | 21 (41%) | |
Etiology | ||||
CVA6 | 81 (80%) | 45 (90%) | 36 (70%) | 0.01 |
Sites | ||||
Limbs | 98 (97%) | 49 (98%) | 49 (96%) | 1.00 |
Arm/Leg/Thigh | 71 (70%) | 35 (70%) | 36 (70%) | 1.00 |
Trunk | 29 (29%) | 21(42%) | 8 (16%) | 0.004 |
Buttocks | 31 (31%) | 17 (34%) | 14 (27%) | 0.52 |
Face | 40 (41%) | 22 (44%) | 18 (35%) | 0.42 |
Ear lobes | 11 (11%) | 6 (12%) | 5 (10%) | 0.76 |
Perioral area | 26 (26%) | 16 (32%) | 10 (20%) | 0.18 |
Symptoms | ||||
Fever | 80 (80%) | 40 (80%) | 39 (76%) | 0.81 |
Sore throat | 59 (58%) | 33 (66%) | 26 (51%) | 0.16 |
Cough/rhinorrhea | 27 (27%) | 14 (28%) | 13 (25%) | 0.83 |
Vomit/diarrhea | 17 (17%) | 6 (12%) | 11 (22%) | 0.29 |
Skin lesions | ||||
Itchiness | 32 (32%) | 22 (44%) | 10 (20%) | 0.01 |
Desquamation | 1 (1%) | 1 (2%) | 0 (0%) | 0.50 |
Pigmentation | 6 (9%) | 5 (10%) | 1 (2%) | 0.11 |
Prickle | 2 (2%) | 2 (4%) | 0 (0%) | 0.24 |
Myoclonic jerks | 14 (14%) | 5 (10%) | 9 (18%) | 0.39 |
Myalgia | 2 (2%) | 2 (4%) | 0 (0%) | 0.24 |