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Table 2 Transmission and infection of 2009 A(H1N1) IV aerosol in pig model and guinea pig model

From: Airborne spread and infection of a novel swine-origin influenza A (H1N1) virus

 

Inoculated animals

DC animals§

AI animals§

Virus in nasal wash#(log10peak copies/ml)

Sero- conversion*

Virus in nasal wash#(log10peak copies/ml)

Sero- conversion*

Virus in nasal wash#(log10peak copies/ml)

Sero- conversion*

Pigs

1

3/3(5.3-6.1)

3/3(640–2560)

3/3(4.9-5.6)

3/3(320–1280)

2/3(5.5-6.0)

2/3(640–1280)

 

2

3/3(5.1-5.8)

3/3(640–1280)

2/3(5.1-5.6)

2/3(320–640)

1/3(4.9)

1/3(640)

Guinea Pigs

1

5/5(4.3-5.2)

5/5(640–1280)

4/5(4.2-4.8)

4/5(640–1280)

2/5(3.8-5.1)

2/5(320–640)

 

2

5/5(5.4-6.2)

5/5(320–1280)

3/5(4.7-5.8)

3/5(320–1280)

3/5(4.1-6.2)

3/5(320–1280)

  1. §DC direct contact; AI aerosol infection; #Virus titers are expressed as mean log10peak copies/ml; *Hemagglutination inhibition(HI)assay was performed with homologous virus and turkey red blood cells. No. of positive animals and HI range indicated.