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Table 1 Number of peptides, proteins, log 2 Infected: Mock (I:M) ratio means and standard deviation, and Z-scores of SILAC-measured HeLa cell proteins after T3D infection

From: HeLa cell response proteome alterations induced by mammalian reovirus T3D infection

 

Cytosol

Nuclei

 

Run #1

Run #2

Run #1

Run #2

Total number of peptide pairs1

22,591

34,393

8,011

8,974

Total number of proteins2

2,067

2,787

670

728

Number of proteins analysed3

1,987

2,684

635

686

Mean Log2 I:M ratios

0.0147

0.0126

0.0004

0.0187

Standard deviation of Log2 I:M ratios

0.3382

0.4211

0.4664

0.3423

Number of proteins at Z-score cutoff of: ± 1.960σ (95%)

33, 224

50, 20

7, 4

20, 12

± 2.576σ (99%)

24, 11

29, 11

5, 2

14, 8

± 3.291σ (99.9%)

14, 7

23, 8

2, 2

8, 4

  1. 1 Total number of H:L peptide pairs for all proteins identified at confidence level ≥ 99%.
  2. 2 Total number of proteins identified at confidence level ≥ 99%.
  3. 3 Number of proteins analyzed after those identified by only a single peptide, as well as possible contaminants, removed.
  4. 4 First value is number of up-regulated proteins outside the indicated confidence level; second number is number of down-regulated proteins outside the indicated confidence level.