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Table 1 Receptor repertoire of tested cell lines

From: Examination of soluble integrin resistant mutants of foot-and-mouth disease virus

Cell Line

αvβ1

αvβ3

αvβ6

αvβ8

HS

Reference

LFBK

+

+

+

*

+

Figure1 (this paper);[29]

CHO K1

-

-

-

-

+

[30–37]

CHO 677

-

-

-

-

-

[21, 30, 38–41]

IBRS2

-

-

-

+

-

[16, 42]

COS-1

*

-

-

-

+

Figures3 and6 (this paper);[7, 36, 37]

  1. + Confirmed expression of the receptor molecule on the cell line indicated.
  2. - Confirmed lack of expression of the receptor molecule on the cell line indicated.
  3. * Unclear if the receptor molecule is expressed on the cell line indicated.
  4. The receptor profile of αvβ1, αvβ3, αvβ6, αvβ8, and HS on 6 cell lines used was tabulated with references to studies that directly demonstrated the receptor profile or did so indirectly by virus growth profiles.
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Virology Journal

ISSN: 1743-422X