Figure 5
From: Examination of soluble integrin resistant mutants of foot-and-mouth disease virus
Structural prediction of the effect of the A-SIR amino acid substitutions on the G-H loop. Depicted are 2 angles (A and B) of models of the VP1 G-H loop of A24 Cruzeiro and representative class I and class II A-SIRs. RGD motif is indicated, and residues are colored: arginine (R), blue; glycine (G), green; aspartic acid (D), red. RGD + 4 position (L/P + 4) is violet. Black arrows indicate altered directionality of the amino acid side chains in A-SIR RGD/RDD sites.