Figure 2
From: Examination of soluble integrin resistant mutants of foot-and-mouth disease virus
A-SIR mutant generation. A. Schematic of A-SIR mutant production. B. Comparison of the plaque morphology and titers achieved of A- SIRs relative to A24 Cruzeiro after pre-treatment and co-incubation with ssαvβ6 on LFBK (top panel) and CHO K1 (bottom panel) cells for 24 h. SIR #42 was the only virus that amplified on CHO 677 cells (right box). Titers represent PFU/mL. C. WT and A-SIR viruses were co-incubated with increasing concentrations of ssαvβ6 on LFBK monolayers for 24 h, and the calculated titers were subsequently plotted.