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Figure 5 | Virology Journal

Figure 5

From: The modulation of apoptosis by oncogenic viruses

Figure 5

EBV genome. Location and transcription of the EBV latent genes on the double-stranded viral DNA episome. The bottom arrows represent coding exons for each of the latent proteins; the latent proteins include the six nuclear antigens (EBNAs 1, 2, 3A, 3B and 3C, and EBNA-LP) and the three latent membrane proteins (LMPs 1, 2A, 2B). EBNA-LP is transcribed from variable numbers of repetitive exons. The arrows with the discontinuous lines close together at the top represent the highly transcribed nonpolyadenylated RNAs EBER1 and EBER2; their transcription is a consistent feature of latent EBV infection. EBNAs are transcribed from either the Cp or Wp promoter.

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Virology Journal

ISSN: 1743-422X