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Table 4 Immunohistochemical detection of viral antigen in lymph nodes of inoculated mice

From: In vivo characterization of chimeric PCV DNA clones containing heterogeneous capsid protein nuclear localization signals (NLS)

Group

Inoculuma

No. of IHC positive mice /no. tested at dpib:

Ā Ā 

28

42

1

MEM

0/4(0.0)I

0/4(0.0)I

2

PCV1 DNA

0/4(0.0)I

0/4(0.0)I

3

PCV2 DNA

3/4(0.75)II

4/4(1.0)II

4

PCV12 DNA

1/4(0.25)I

1/4(0.25)I

5

PCV1-NLS2 DNA

0/4(0.0)I

0/4(0.0)I

6

PCV2-NLS1 DNA

0/4(0.0)I

0/4(0.0)I

  1. aMEM was used as a negative control.
  2. bFour mice were tested in each group at different time points following inoculation. Values in parentheses are mean levels of positive signal in lymph nodes. Different superscripts (I and II) indicate that the mean scores differ significantly between the groups (Pā€‰<ā€‰0.05).