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Table 3 Significant positions of polyprotein of 31 strains

From: Complete genome sequencing and analysis of six enterovirus 71 strains with different clinical phenotypes

Region

Position

Amino acid

Strains with neurovirulence

Strains without neurovirulence

VP1

814

Val/Ile(16/0)*

Val/Ile(10/5)

3A

1148

Val/Ile(16/0)

Val/Ile(11/4)

3C

1728

Ala/Cys/Val (16/0/0)

Ala/Cys/Val (10/1/4)

  1. *Val/Ile(16/0): in all 16 strains with neurovirulence, 16 of them were ValP814 and none of them was IleP814