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Table 1 Virus, clinical signs, virus replication, and seroconversion of tree shrews

From: The tree shrew provides a useful alternative model for the study of influenza H1N1 virus

Virus Body weight (g)a Body temperature (°C)b Nasopharyngeal secretion Peak mean nasal wash titer±SD (day)d Number positive/total (average logTCID50/mL)e Seroconversion(HI titer)f
      Nasal mucosa Tracheal Lung  
A/PR8/34 99.77±0.42 39.78±0.44 Positive (3/3)c 2.94±0.92 (2) (3/3) (1.89) (0/3) (0/3) (3/3) 80,80,320
GZ/02/09 98.92±0.63 40.26±0.55 Positive (3/3) 3.00±0.33 (2) (3/3) (1.90) (0/3) (0/3) (3/3) 80,160,640
S-OIV/GZ/07/09 100.24±0.49 40.57±0.59 Positive (3/3) 4.24±0.25 (1) (3/3) (2.17) (0/3) (0/3) (3/3) 80,160,640
Control 99.46±0.36 38.20±0.47 No 0 (0/3) (0/3) (0/3) (0/3) 0,0,0
  1. a Bodyweight on day o.
  2. b Average body temperature on day 2 p.i.
  3. c Number of inoculated tree shrews/total number.
  4. d Peak nasal wash titers are expressed as the mean±SD log10 TCID50/mL.
  5. e Virus titers in different tissues was detected on day 2 p.i.
  6. f Serum was collected on day 14 p.i., and homologous strains were used with chicken RBCs in HI assay.