Figure 5
From: Neutralization sensitivity of HIV-1 subtype B’ clinical isolates from former plasma donors in China
Neutralization sensitivity of AH259V and neutralizing activity of AH259P. The neutralization sensitivity of AH259V to the broadly neutralizing monoclonal antibodies ( F105, IgG1B12, 17b, 447-52D and 2F5) (a) and the neutralizing activity of AH259P against the primary HIV-1 isolates, including 92RW002 (subtype A, R5), 92US657 (subtype B, R5), 93IN101 (subtype C, R5), RU570 (subtype G, R5), and BCF02 (group O, R5) (b) were determined using a neutralizing assay for HIV-1 infection in PBMCs as described in the Methods. The dotted line indicated that (a) the initial concentration of bnmAbs is ranging from 50μg/ml, and IC50 >50μg/ml were treated as 50; (b) the initial dilutions of plasma is ranging from 1:8, and the ID50 titers (1/x) of < 8 were treated as 8.